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KMID : 1100220040030020077
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Dementia and Neurocognitive Disorders
2004 Volume.3 No. 2 p.77 ~ p.81
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Memory Tests in Animals
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Han Jung-Soo
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Abstract
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Good animal models for memory impairments by aging or the diseases are necessary for the understanding of the fundamental cognitive mechanisms, and studying the causes of neurological diseases related memory disorders and the development of new drugs. It is widely accepted that the hippocampus and the related brain areas mediate declarative memory in humans. The rats with hippocampal damages fail to learn so called ‘the hippocampal-dependant task’, such as water maze task, radial arm maze and context fear conditioning. It was also pointed out that animal’s strains and characteristics of memory task should be considered before the start of experiments for accessing memory nature or effects of a drug on the memory with rats or mice.
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KEYWORD
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Memory, Hippocampus, Animal, Water maze
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